Microbial associates of Endocervical swabs of women with Pelvic inflammatory disease and fertility disorders

Microbial associates of Endocervical swabs of women with Pelvic inflammatory disease and fertility disorders

Authors: OBIAJURU  I. O. C* OGBULIE J. N and  ONUOHA C. A

Abstract:

The microbial associates of endocervical swabs of women with pelvic inflammatory disease (PID) and fertility disorders in Orlu Imo State was studied between October 2014 and February 2015. Endocervical swab (ECS) and High vaginal (HVS) were collected from 210 women aged 20 years and above at the obstetrics and Gynaecology Department Imo State University Teaching Hospital Orlu. The samples were examined bacteriologically using culture technique. The bacterial isolates were subjected to antibiotic sensitivity tests using commercially prepared antibiotic discs. The findings showed that 168(80%) HVS and 111(5.9%) ECS were infected with different species of bacteria and fungi. The prevalence of microbial infections was higher (80%) in HVS than endocervical swabs (5.9%). The most prevalent bacterial isolate was omitted in Staphylococcu aureus while the least prevalent isolates were Pseudomonas aeruginosa (1.4%) and Streptococcus species (1.4%). Prevalence of infection was higher amongst older women age 41 and above than younger women aged 20– 40 years. Also prevalence of infection was higher amongst women with pelvic inflammatory disease (8.3% HVS and 57.9% ECS) than those with fertility disorders (75% HVS and 45%ECS). Staphylococcus aureus and Pseudomonas aeruginosa exhibited the highest percentage of susceptibility to Ceftazidine. Streptococcus agalactiae and Escherichia coli exhibited the highest percentage of susceptibility to Azetronem. Klebsiella species exhibited the lowest percentage of susceptibility to erythromycin. Prevalence of multi antibiotic resistance was higher amongst isolates from High vaginal swabs than isolates from endocervical swabs. Pseudomonas aeruginosa exhibited the highest prevalence (3.3%) of multi – antibiotic resistance followed by Escherichia coli (20.8%). The findings of this study suggest that pelvic inflammatory disease and fertility disorders May be caused or complicated by microbial infections.  

DownloadOBIAJURU  I. O. C et al SPJPBS.2017. 5(1)017-028